University of Helsinki
The University of Helsinki (UH), founded in 1640, is Finland’s oldest and largest institution of higher education. It is a leading multidisciplinary university known for its high-quality research and teaching in areas such as the humanities, social sciences, natural sciences, medicine, and law. The University serves a community of over 30,000 students and staff. It is consistently ranked among the top 1% of universities worldwide and plays a key role in promoting innovation and sustainability.
Role within GreenNanoBone
In the context of GreenNanoBone, UH participates in molecular studies related to the MRONJ simulation in vitro (WP9) and the validation of GreenNanoBone in 3D MRONJ in vitro models (WP10). UH performs transcriptomics analysis of 3D in vitro models exposed to Bisphosphonates (BPs). UH leads the task for the Comparative analysis of omics data (Task 12.5), integrating multi-omics data (bulk RNASeq, scRNASeq, proteomics) derived from in vitro, in vivo, and human samples using network-based methods to extrapolate the biomaterial’s mechanism of action