Overview

About GreenNanoBone

While cancer survival rates continue to rise, certain long-term treatment-related complications remain challenging. One of them is Medication-Related Osteonecrosis of the Jaw (MRONJ), a side effect of bisphosphonates that leads to bone death, infections and ultimately the inability to eat. To prevent and treat this condition, GreenNanoBone will develop a biocompatible, antimicrobial hydrogel from plant-based food industry waste. Designed for injection and 3D printing, it promotes tissue regeneration and reduces antibiotic use. The sustainable approach supports circular economy goals, with the hydrogel expected to reach preclinical validation by project’s end.

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start
start01. June 2025
Duration
Duration48 months
Budget
Budget€ 8.6 Mio

International Cooperation

Coordinated by the University of Liverpool, the interdisciplinary approach of GreenNanoBone brings together 18 partners from all over Europe. This diverse team including chemists, biomaterials scientists, biologists, clinicians, social scientists and health economists, are joining forces to develop innovative treatments and prevention methods for MRONJ.

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A Pan-European Healthcare Project

GreenNanoBone exemplifies the synergies between Horizon Europe Pillar II Clusters. GreenNanoBone is contributing to creating lasting impact by:

  • Improving cancer care Addressing critical unmet medical needs in oncology (Cluster 1: Health).

  • Driving sustainability in manufacturing Developing climate-neutral and circular bio-based production methods (Cluster 5: Climate, Energy and Mobility).

  • Innovating with food waste Transforming agricultural food waste into high-value medical materials (Cluster 6: Food, Bioeconomy, Natural Resources, Agriculture and Environment).

By turning leftover potato pulp from the starch industry into advanced biomaterials, GreenNanoBone actively supports Europe’s Green Transition. This "design for circularity" approach aims to significantly reduce the environmental footprint of medical manufacturing, leading to scalable, cleaner production methods.

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